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Decellularized Extracellular Matrix(dECM) Technology Platform

Decellularized extracellular matrix (dECM) is a natural material purified by removing cells, antigens and other components from animal or human tissues using different decellularisation techniques such as physical, chemical and biological.And it has the main components of extracellular matrix(ECM). Extracellular matrix (ECM) is the microenvironment for cell survival, and together with cells, it forms human tissues and organs, and its complex three-dimensional network structure consisting of numerous proteins and polysaccharides provides stable signal transmission and structural support for tissues and organs. Because of its ability to play a better repair and regeneration efficacy, decellularized extracellular matrix is considered to be a new generation of biomaterials suitable for regenerative medicine, which plays an increasingly important role in the fields of tissue repair, organ transplantation and regenerative medicine, and has great potential for development.

The technology platform, relying on a number of core patented technologies, has key technical capabilities in the preparation of decellularized extracellular matrix materials for different tissues and organs, the development of sheet biomedical materials and gel biomedical materials, the evaluation of biocompatibility of materials, the evaluation of functional restorative effects, the research and development of biological regenerative materials with various advantages, such as low immunogenicity, absorption and metabolism.And the platform also reserves various research and development technologies of new generation mainstream medical materials such as hyaluronic acid, PLA, PLLA, pectin, PCL, peptides, polyethylene, PVA, polyurethane, polytetrafluoroethylene, microcrystalline calcium, chitosan, hydroxyapatite, humanized collagen, etc. Its products are widely used in the fields of tissue repair, surgical patches, medical aesthetic fillers and cell therapy and so on, in various forms to meet different clinical needs.

Technical Advantage
Highly Effective

Decellularized extracellular matrix is naturally biomimetic to provide an optimal microenvironment for cell growth.

The composition and structure of normal tissue decellularized extracellular matrix is retained after tissue decellularization, which can replace or repair damaged tissues.

Decellularized extracellular matrix is rich in cytokines and functional polypeptides, with the ability of tissue microenvironment regulation and Promoting Vascularization.

It Accelerates the healing cycle of damaged tissues.

High Safety

Low immunogenicity: more complete degreasing and decellularisation.

No disruption of decellularized extracellular matrix composition and structure

It reduces rejection with the human body and minimises the chance that 100% of the degradation products will be absorbed and metabolised by the human body.

Novelty Products

it is a new biomaterial, derived from the porcine omentum, which is easily accessible.

No biomaterial products with the same raw material are available domestically or internationally.

Customised product forms according to market demand, mainly film and gels.

Core Technology

A Decellularisation Technology for Preserving the Active Ingredients of the Natural Decellularized Extracellular Matrix

α-Gal Antigen Removal Technology

A Cross-linking Techniques for Decellularized Extracellular Matrix

Freeze-drying Moulding Technology

Application
  • Applied to the Repair of Various Tissues and Organs: skin, organs, bone, cartilage, tendons, etc.

  • All Kinds of Surgical Patches: dura mater, hernia, pelvic floor repair, etc.

  • Excellent Tissue Filler Materials: scar treatment, facial plastic surgery and other aesthetic fields.

  • Adjuvant Treatment for Cell Therapy: injectable carriers for fat cells, stem cells and so on, to improve the efficiency of cell therapy

  • Adust the Form According to Indication: biofilm, sponge, gel, granules, etc.

Web:www.dkbiotech.com.cn

Add:Building 6, No.9 Tianfu Street, Daxing Bio-pharmaceutical Industry Base, 

Zhongguancun Science and Technology Park, Daxing District, Beijing

Hotline:(+86)400-080-9519

Email:services@healtech.com.cn


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